Catalog No.ProductsDescription
MOC-00007Axitinib CAS 319460-85-0Axitinib is a selective and oral inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases 1, 2 and 3.
MOC-00027Altiratinib CAS 1345847-93-9Altiratinib(DCC-2701; DP-5164) is a novel c-MET/TIE-2/VEGFR inhibitor.
MOC-00053SGX523 CAS 1022150-57-7GX-523 is a novel, potent, ATP-competitive, and highly-selective Hepatocyte growth factor receptor (MET) inhibitor with IC50 value of 4 nM.
MOC-00055Acalabrutinib (ACP-196) CAS 1420477-60-6Acalabrutinib (ACP-196) is a second-generation, selective, irreversible inhibitor of BTK (Bruton’s tyrosine kinase)
MOC-00073G-749 CAS 1457983-28-6G-749 is a novel FLT3 inhibitor.
MOC-00081SU11274 CAS 658084-23-2SU11274 is a potent and selective inhibitor of Met kinase with IC50 value of 10nM.
MOC-00089Savolitinib (Volitinib) CAS 1313725-88-0Savolitinib, also known as Volitinib, AZD6094 or HMPL-504, is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity.
MOC-00127GNF-7 CAS 839706-07-9GNF-7 inhibits Bcr-Abl WT and Bcr-Abl T315I with IC50 of 133 nM and 61 nM, respectively.
MOC-00132PF-06463922 CAS 1454846-35-5PF-06463922 is a potent and selective ALK/ROS1 inhibitor.
MOC-00133GZD824 Dimesylate CAS 1421783-64-3GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
MOC-00134GZD824 CAS 1257628-77-5GZD824 is a novel orally bioavailable Bcr-Abl inhibitor.
MOC-00135E7050 CAS 928037-13-2E7050(Golvatinib) is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM.
MOC-00141ANA-12 CAS 219766-25-3ANA-12 is a potent and selective antagonist of TrkB
MOC-00149SU-5614 CAS 1055412-47-9SU5614 is a potent and selective FLT3 inhibitor.
MOC-00154FGFR4-IN-1 CAS 1708971-72-5FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM.
MOC-00246LY2801653 CAS 1206799-15-6LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM).
MOC-00248Defactinib (PF-04554878) CAS 1073154-85-4Defactinib(VS-6063; PF-04554878) is a potent FAK phosphorylation inhibitor; overcomes YB-1–mediated paclitaxel resistance by an AKT-dependent pathway.
MOC-00251Tandutinib CAS 387867-13-2Tandutinib (MLN518, CT53518) is a potent antagonist of FLT3 with an IC50 value of 0.22 μM.
MOC-00255Fostamatinib disodium CAS 1025687-58-4R788 (Fostamatinib), a prodrug of the active metabolite R406, is a potent Syk inhibitor with IC50 of 41 nM.
MOC-00256Fostamatinib (R788) CAS 901119-35-5R788 (Fostamatinib), a prodrug of the active metabolite R406, is a potent Syk inhibitor with IC50 of 41 nM.
MOC-00258FGF401 (FGF-401) CAS 1708971-55-4FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4).